Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40035 | 0.79 | TSHR (0.48) | TSHRALDH1A1MAPK1TAAR1CES2 | |
| SCHEMBL30488629 | 0.72 | CETP (0.33) | ALDH1A1KIF11 | |
| SCHEMBL3126195 | 0.69 | ALDH1A1 (0.43) | TSHRALDH1A1TAAR1CES2MGLL | |
| SCHEMBL30658161 | 0.68 | TSHR (0.44) | TSHRALDH1A1MAPK1TAAR1CES2 | |
| SCHEMBL5459115 | 0.66 | CES2 (0.42) | TSHRALDH1A1MAPK1CES2IDO1 | |
| Hydrochloric Acid SCHEMBL30732529 | 0.66 | KIF11 (0.43) | TSHRALDH1A1TAAR1CES2MGLL | |
| SCHEMBL30828340 | 0.64 | TAAR1 (0.52) | TSHRALDH1A1MAPK1TAAR1IDO1 | |
| Bromide SCHEMBL20184810 | 0.63 | TSHR (0.48) | TSHRALDH1A1MAPK1TAAR1CES2 | |
| SCHEMBL7849448 | 0.63 | HDAC8 (0.42) | ALDH1A1KIF11 | |
| Iodide SCHEMBL20184829 | 0.63 | TSHR (0.48) | TSHRALDH1A1MAPK1TAAR1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655700-B | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2023-07-18 | — | — | CN | disclosed |