Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40035 | 0.79 | TSHR (0.48) | CES2IDO1TSHRALDH1A1TDP1 | |
| SCHEMBL440959 | 0.78 | CES2 (0.58) | CES2IDO1TSHRALDH1A1CYP3A4 | |
| SCHEMBL432591 | 0.76 | CES2 (0.41) | CES2IDO1TSHRALDH1A1CYP3A4 | |
| SCHEMBL3126195 | 0.76 | ALDH1A1 (0.43) | CES2TSHRALDH1A1 | |
| SCHEMBL5599436 | 0.76 | CES2 (0.41) | CES2IDO1TSHRALDH1A1CYP3A4 | |
| SCHEMBL3162653 | 0.76 | GABRA1 (0.46) | TSHRALDH1A1HPGDALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL30732529 | 0.72 | KIF11 (0.43) | CES2TSHRALDH1A1 | |
| SCHEMBL11600999 | 0.71 | CES2 (0.46) | CES2IDO1TSHRALDH1A1CYP3A4 | |
| SCHEMBL11683794 | 0.71 | CES2 (0.46) | CES2IDO1TSHRALDH1A1CYP3A4 | |
| SCHEMBL3786224 | 0.71 | RAPGEF4 (0.47) | CES2IDO1TSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486912-A | Process method for synthesizing sodium tetra (3, 5-bis (trifluoromethyl) phenyl) borate | 大连双硼医药化工有限公司 | 2024-02-02 | — | — | CN | claimed |
| EP-1673329-B1 | PROCESS FOR THE PREPARATION 3,5-BIS(TRIFLUOROMETHYL)BENZYLALCOHOL | MITENI SPA (IT) | 2007-09-12 | — | — | EP | claimed |
| US-20070135662-A1 | Process for the preparation of 3,5- bis(trifluoromethyl)benzylalcohol | MITENI S.P.A. (IT) | 2007-06-14 | — | — | US | claimed |
| CN-117486912-A | Process method for synthesizing sodium tetra (3, 5-bis (trifluoromethyl) phenyl) borate | 大连双硼医药化工有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-9834569-B2 | Process for producing tetrakis(Faryl)borate salts | ALBEMARLE CORPORATION (US) | 2017-12-05 | — | — | US | disclosed |
| US-20170313725-A1 | Process For Producing Tetrakis(F aryl)Borate Salts | W. R. GRACE & CO-CONN. | 2017-11-02 | — | — | US | disclosed |
| US-9738662-B2 | Process for producing tetrakis(F aryl)borate salts | ALBEMARLE CORPORATION (US) | 2017-08-22 | — | — | US | disclosed |
| EP-2925766-B1 | PROCESS FOR PRODUCING TETRAKIS(F ARYL)BORATE SALTS | ALBEMARLE CORP (US) | 2016-07-13 | — | — | EP | disclosed |
| EP-2925766-A1 | PROCESS FOR PRODUCING TETRAKIS(F ARYL)BORATE SALTS | Albemarle Corporation (US) | 2015-10-07 | — | — | EP | disclosed |
| US-20150259362-A1 | Process For Producing Tetrakis(F aryl)Borate Salts | W. R. GRACE & CO.-CONN. | 2015-09-17 | — | — | US | disclosed |
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2014-08-21 | — | — | US | disclosed |
| WO-2014085058-A1 | PROCESS FOR PRODUCING TETRAKIS(FARYL)BORATE SALTS | ALBEMARLE CORPORATION (US) | 2014-06-05 | — | — | WO | disclosed |
| EP-1673329-B1 | PROCESS FOR THE PREPARATION 3,5-BIS(TRIFLUOROMETHYL)BENZYLALCOHOL | MITENI SPA (IT) | 2007-09-12 | — | — | EP | disclosed |
| US-20070135662-A1 | Process for the preparation of 3,5- bis(trifluoromethyl)benzylalcohol | MITENI S.P.A. (IT) | 2007-06-14 | — | — | US | disclosed |
| EP-1312605-B1 | Method for producing biaryl compounds | SUMITOMO CHEMICAL CO (JP) | 2007-04-25 | — | — | EP | disclosed |
| US-7122711-B2 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-17 | — | — | US | disclosed |
| EP-1673329-A1 | PROCESS FOR THE PREPARATION 3,5-BIS(TRIFLUOROMETHYL)BENZYLALCOHOL | MITENI S.p.A. (IT) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005035472-A1 | PROCESS FOR THE PREPARATION 3,5-BIS(TRIFLUOROMETHYL)BENZYLALCOHOL | MITENI S.P.A. (IT) | 2005-04-21 | — | — | WO | disclosed |
| US-20030158419-A1 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-21 | — | — | US | disclosed |
| EP-1312605-A1 | Method for producing biaryl compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158419-A1 | Method for producing biaryl compound | B2M, BMI1, CYP2W1 | CES2 844/4885IDO1 136/4885TSHR 1588/4885 |
| US-20140235867-A1 | METHOD FOR PRODUCING ALPHA-HYDROXY KETONE COMPOUND | HSD17B7, BCKDK, HSD11B1 | CES2 690/4885IDO1 3687/4885TSHR 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.