Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | ULK1 | O75385 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11919268 | 1.00 | ASPH (0.36) | ASPHULK1CFTRSYKAURKA | |
| SCHEMBL29395367 | 0.78 | PIK3R1 (0.36) | ASPHULK1CFTR | |
| SCHEMBL19837518 | 0.78 | NOTUM (0.38) | ASPH | |
| SCHEMBL16656835 | 0.78 | HPGD (0.35) | ASPHULK1CFTR | |
| SCHEMBL1440021 | 0.78 | PIK3CD (0.41) | ASPHCFTR | |
| SCHEMBL28682675 | 0.78 | ASPH (0.34) | ASPHULK1CFTR | |
| SCHEMBL432680 | 0.78 | PIK3R1 (0.36) | ASPHULK1CFTR | |
| SCHEMBL31214077 | 0.78 | PIK3CD (0.41) | ASPHCFTR | |
| SCHEMBL14392743 | 0.78 | AGBL2 (0.35) | ASPH | |
| SCHEMBL16770544 | 0.74 | NOTUM (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655700-B | Oxadiazolopyridine derivatives as ghrelin O-acyltransferase (GOAT) inhibitors | 勃林格殷格翰国际有限公司 | 2023-07-18 | — | — | CN | disclosed |