Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25274071 | 1.00 | PARP1 (0.52) | PARP1MEN1KMT2ARXFP1CACNA1B | |
| SCHEMBL1663221 | 0.87 | PARP1 (0.52) | PARP1MEN1KMT2ARXFP1CACNA1B | |
| SCHEMBL31289499 | 0.86 | DGAT1 (0.58) | PARP1MEN1KMT2ARXFP1CACNA1B | |
| SCHEMBL10325591 | 0.84 | HTR3E (0.51) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30533210 | 0.82 | MEN1 (0.73) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL1655753 | 0.82 | MEN1 (0.73) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL14669422 | 0.81 | PARP1 (0.44) | PARP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL532061 | 0.81 | ACHE (0.68) | PARP1KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL19137933 | 0.81 | RHEB (0.58) | PARP1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL159873 | 0.80 | ALDH1A1 (0.74) | MEN1KMT2ARXFP1CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023110765-A1 | BENZIMIDAZOLE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF INFECTIOUS DISEASES | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2023-06-22 | — | — | WO | disclosed |