Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27694230 | 1.00 | P2RX7 (0.47) | P2RX7KMT2AMEN1GABRA1GABRG2 | |
| SCHEMBL6602091 | 0.79 | P2RX7 (0.56) | P2RX7KMT2AMEN1GABRA1GABRG2 | |
| SCHEMBL5026814 | 0.79 | P2RX7 (0.55) | P2RX7KMT2AMEN1AHRFAAH | |
| SCHEMBL27956798 | 0.79 | GABRG2 (0.38) | KMT2AGABRA1GABRG2GABRB3GABRA3 | |
| SCHEMBL27539765 | 0.78 | P2RX7 (0.55) | P2RX7KMT2AMEN1GABRA1GABRG2 | |
| Hydrochloric Acid SCHEMBL29205819 | 0.78 | P2RX7 (0.55) | P2RX7KMT2AMEN1GABRA1GABRG2 | |
| SCHEMBL2652708 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1GABRA1GABRG2GABRB3 | |
| SCHEMBL27708372 | 0.76 | P2RX7 (0.49) | P2RX7KMT2AMEN1AHRFAAH | |
| SCHEMBL29550139 | 0.76 | ALDH1A1 (0.55) | KMT2AMEN1GABRA1GABRG2GABRB3 | |
| SCHEMBL24927890 | 0.76 | P2RX7 (0.45) | P2RX7KMT2AMEN1FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025326-A | Heterocyclic compound of bifunctional chimera for targeting and degrading androgen receptor and application thereof | 广东东阳光药业股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| WO-2025011623-A1 | CYANOQUINOLINE-TARGETING PROTEIN DEGRADATION MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海壹迪生物技术有限公司 | 2025-01-16 | — | — | WO | disclosed |
| CN-112010858-B | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-07-18 | — | — | CN | disclosed |