SCHEMBL30489293

SCHEMBL30489293

COc1ccc2c(c1)CC(C)C(=O)N2Cc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 2/20 0.48
XIAP P98170 1/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
PARK7 Q99497 1/20 0.46
PTGDR2 Q9Y5Y4 1/20 0.45
TDP1 Q9NUW8 2/20 0.45
DRD2 P14416 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HTR2B P41595 1/20 0.44
SIGMAR1 Q99720 1/20 0.44
GSK3B P49841 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MTNR1A P48039 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28995167 1.00 MEN1 (0.48) MEN1KMT2ALMNAXIAPCRHBP
SCHEMBL5221385 0.85 L3MBTL1 (0.54) MEN1KMT2ALMNADRD2GSK3B
SCHEMBL30100700 0.85 L3MBTL1 (0.54) MEN1KMT2ALMNADRD2GSK3B
SCHEMBL30806781 0.85 MEN1 (0.46) MEN1KMT2ALMNAXIAPCRHBP
SCHEMBL30489297 0.84 KMT2A (0.52) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL28995171 0.84 KMT2A (0.52) MEN1KMT2ALMNAALDH1A1MAPK1
SCHEMBL30489354 0.84 ALDH1A1 (0.49) MEN1KMT2APTGDR2ALDH1A1
SCHEMBL28995163 0.84 ALDH1A1 (0.49) MEN1KMT2APTGDR2ALDH1A1
SCHEMBL31398271 0.83 PARK7 (0.46) MEN1KMT2APARK7GSK3BALDH1A1
SCHEMBL28995174 0.82 ALDH1A1 (0.53) MEN1KMT2AXIAPSIGMAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116043243-B Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2025-02-18 CN disclosed
CN-116043243-A Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2023-05-02 CN disclosed