SCHEMBL30489337

SCHEMBL30489337

CC1Cc2ccccc2N(C)C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.56
HPGD P15428 2/20 0.56
ACHE P22303 1/20 0.47
ADRA1A P35348 2/20 0.46
ADRA2A P08913 1/20 0.46
ADRA2B P18089 1/20 0.46
ADRA2C P18825 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2A P28223 1/20 0.46
HTR2C P28335 1/20 0.46
SLC6A4 P31645 1/20 0.46
HRH1 P35367 1/20 0.46
HTR2B P41595 1/20 0.46
KCNH2 Q12809 1/20 0.46
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
ADRA1D P25100 1/20 0.46
ADRA1B P35368 1/20 0.46
AADAT Q8N5Z0 2/20 0.45
NOTUM Q6P988 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9560256 1.00 MAPT (0.56) MAPTHPGDACHEADRA1AADRA2A
SCHEMBL12340980 0.82 ADRA1A (0.44) MAPTHPGDADRA1AADRA2AADRA2B
SCHEMBL25556401 0.82 DRD4 (0.48) MAPTHPGDDRD2DRD4BRD4
SCHEMBL13502655 0.82 DRD4 (0.48) MAPTHPGDDRD2DRD4BRD4
SCHEMBL28136146 0.80 DRD4 (0.51) ADRA1AADRA2AADRA2BADRA2CSLC6A2
SCHEMBL28865012 0.80 ACHE (0.46) MAPTHPGDACHESLC6A2HTR2A
SCHEMBL28247488 0.80 ADRA1A (0.45) HPGDADRA1AADRA2AADRA2BADRA2C
SCHEMBL28136177 0.80 ADRA1A (0.45) HPGDADRA1AADRA2AADRA2BADRA2C
SCHEMBL22527291 0.80 DRD4 (0.43) MAPTHPGDDRD2DRD4NOTUM
Hydrochloric Acid SCHEMBL4800182 0.79 AADAT (0.63) ADRA1AADRA2AADRA2BADRA2CSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116043243-B Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2025-02-18 CN disclosed
CN-116043243-A Method for electrochemically synthesizing 3, 4-dihydro-quinolinone compounds 桂林电子科技大学 2023-05-02 CN disclosed