Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | TEK | Q02763 | 4/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.35 |
| ▸ | HTR5A | P47898 | 4/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3050294 | 0.89 | HDAC6 (0.42) | HDAC1HTR5ASLC2A1HTR1ADRD2 | |
| Trifluoroacetic Acid SCHEMBL3041840 | 0.88 | CCR2 (0.38) | HDAC1TEKEPHB4HTR5ASLC2A1 | |
| SCHEMBL13136976 | 0.83 | QPCT (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL3046203 | 0.81 | HTR5A (0.46) | HTR5ASLC2A1HTR1ADRD2DRD4 | |
| Trifluoroacetic Acid SCHEMBL3046770 | 0.81 | CCR2 (0.38) | HDAC1TEKEPHB4HTR5ASLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3047584 | 0.81 | CCR2 (0.38) | HDAC1TEKEPHB4HTR5ASLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3039719 | 0.81 | MEN1 (0.43) | HDAC1HTR5ASLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3044503 | 0.80 | HTR5A (0.44) | HTR5ASLC2A1HTR1ADRD2DRD4 | |
| Trifluoroacetic Acid SCHEMBL3044914 | 0.80 | HTR5A (0.39) | HTR5AHTR1ADRD2DRD4HTR1D | |
| Trifluoroacetic Acid SCHEMBL3045182 | 0.80 | HDAC1 (0.43) | HDAC1SLC2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | SMITHKLINE BEECHAM CORPORATION | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222345-A1 | NOVEL COMPOUNDS AS ANTAGONISTS OR INVERSE AGONISTS FOR OPIOID RECEPTORS | OPRL1, OPRM1, OPRK1 | HDAC1 2221/4885TEK 788/4885EPHB4 950/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.