Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.61 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA3 | P07451 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA6 | P23280 | 1/20 | 0.45 |
| ▸ | CA5A | P35218 | 1/20 | 0.45 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27645322 | 0.81 | THRA (0.58) | THRATHRBESR1ESR2NPC1 | |
| SCHEMBL15799777 | 0.80 | THRB (0.57) | THRATHRBMEN1KMT2AESR1 | |
| SCHEMBL7945362 | 0.78 | ESR1 (0.56) | CA2CA12CA1CA7CA9 | |
| SCHEMBL2130368 | 0.75 | CA2 (0.73) | CA2CA12CA1CA7CA9 | |
| SCHEMBL28189045 | 0.74 | PTPN5 (0.54) | THRATHRBCA2CA1SMN1; SMN2 | |
| SCHEMBL29155389 | 0.74 | ESR1 (0.54) | THRATHRBESR1ESR2NPC1 | |
| SCHEMBL3049095 | 0.73 | HSPA5 (0.47) | MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL25528251 | 0.73 | THRB (0.79) | THRATHRB | |
| SCHEMBL16203374 | 0.72 | KLKB1 (0.58) | THRATHRBESR1ESR2 | |
| SCHEMBL9558175 | 0.72 | KMT2A (0.49) | THRATHRBMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1946108-B1 | HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY | SIEMENS HEALTHCARE DIAGNOSTICS (US) | 2014-10-01 | — | — | EP | disclosed |
| US-7785904-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2010-08-31 | — | — | US | disclosed |
| EP-1946108-A2 | HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY | Bayer Healthcare LLC (US) | 2008-07-23 | — | — | EP | disclosed |
| US-20080014660-A1 | High Quantum Yield Acridinium Compounds and Their Uses in Improving Assay Sensitivity | BAYER HEALTHCARE LLC | 2008-01-17 | — | — | US | disclosed |
| US-7309615-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2007-12-18 | — | — | US | disclosed |
| WO-2006130736-A2 | HIGH QUANTUM YIELD ACRIDINIUM COMPOUNDS AND THEIR USES IN IMPROVING ASSAY SENSITIVITY | SIEMENS MEDICAL SOLUTIONS DIAGNOSTICS (US) | 2006-12-07 | — | — | WO | disclosed |
| US-20050221390-A1 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | BAYER HEALTHCARE LLC (US) | 2005-10-06 | — | — | US | disclosed |