Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3046103 | 0.89 | SMN1; SMN2 (0.57) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL3764555 | 0.83 | RAB9A (0.60) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| Hydrochloric Acid SCHEMBL7423557 | 0.81 | RAB9A (0.58) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL18381389 | 0.81 | KMT2A (0.59) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL10403280 | 0.80 | MAPT (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL7455902 | 0.79 | KDM4E (0.50) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL9805593 | 0.77 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL24866430 | 0.77 | KDM4E (0.51) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL15219972 | 0.77 | KDM4E (0.51) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL10403279 | 0.76 | MAPT (0.52) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470861-B2 | Mitochondria-targeted antioxidant prodrugs and methods of use | UNIVERSITY OF ROCHESTER (US) | 2013-06-25 | — | — | US | disclosed |
| US-20100168198-A1 | Mitochondria-targeted antioxidant prodrugs and methods of use | UNIVERSITY OF ROCHESTER | 2010-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168198-A1 | Mitochondria-targeted antioxidant prodrugs and methods of use | TXNRD2, HADHA, PRDX5 | ALDH1A1 477/4885SMN1; SMN2 1471/4885RAB9A 2731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.