Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 7/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PKLR | P30613 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3055522 | 0.85 | KMT2A (0.55) | MEN1ALDH1A1KMT2ASLC40A1SLC22A12 | |
| SCHEMBL3057088 | 0.83 | MEN1 (0.53) | MEN1ALDH1A1KMT2ASLC40A1SLC22A12 | |
| SCHEMBL3063587 | 0.81 | SLC22A12 (0.48) | SLC22A12PTGDR2HTR6NTSR1 | |
| SCHEMBL13139534 | 0.81 | MEN1 (0.47) | MEN1ALDH1A1KMT2ASLC40A1SLC22A12 | |
| SCHEMBL3049391 | 0.81 | KMT2A (0.47) | MEN1ALDH1A1KMT2ASLC40A1SLC22A12 | |
| SCHEMBL13139542 | 0.78 | MEN1 (0.44) | MEN1ALDH1A1KMT2ASLC40A1SLC22A12 | |
| SCHEMBL3051446 | 0.78 | S1PR1 (0.44) | MEN1ALDH1A1KMT2ASLC40A1MCL1 | |
| SCHEMBL13139529 | 0.75 | MEN1 (0.40) | MEN1ALDH1A1KMT2ASLC40A1SLC22A12 | |
| SCHEMBL3057076 | 0.74 | MEN1 (0.38) | MEN1ALDH1A1KMT2ANTSR1 | |
| SCHEMBL3047267 | 0.70 | HTR6 (0.51) | ALDH1A1KMT2AMCL1ACLYHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8492559-B2 | Substituted indole compounds | GRUENENTHAL GMBH (DE) | 2013-07-23 | — | — | US | disclosed |
| US-20100222324-A1 | Substituted Indole Compounds | GRUENENTHAL GMBH (DE) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222324-A1 | Substituted Indole Compounds | BDKRB1, BDKRB2, EDNRB | MEN1 1256/4885ALDH1A1 1551/4885KMT2A 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.