Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | APEX1 | P27695 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.68 |
| ▸ | ALPL | P05186 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | ALPI | P09923 | 1/20 | 0.68 |
| ▸ | ALPG | P10696 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.68 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.57 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6725127 | 0.88 | GABRP (0.62) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL29974497 | 0.81 | KMT2A (1.00) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL14053704 | 0.81 | KMT2A (1.00) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL24840880 | 0.79 | KMT2A (0.72) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL29615754 | 0.77 | KMT2A (0.68) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL30269735 | 0.77 | KMT2A (0.68) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL28104733 | 0.77 | KMT2A (0.78) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL28986431 | 0.76 | CBS (0.78) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL476215 | 0.76 | CBS (0.78) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL29435853 | 0.76 | CBS (0.78) | KMT2APKMMAPTKDM4EAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113563399-B | Method for preparing tiacumicin B iodide and other aromatic iodination products and application thereof | 中国科学院南海海洋研究所 | 2023-06-27 | — | — | CN | disclosed |