Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 1.00 |
| ▸ | PKM | P14618 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | APEX1 | P27695 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | INPPL1 | O15357 | 1/20 | 1.00 |
| ▸ | ALPL | P05186 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | ALPI | P09923 | 1/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | ALPG | P10696 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | MCL1 | Q07820 | 1/20 | 1.00 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.63 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14053704 | 1.00 | KMT2A (1.00) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL28104733 | 0.88 | KMT2A (0.78) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL27974348 | 0.87 | MAPT (0.77) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL29974322 | 0.84 | PPARG (0.81) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL27221221 | 0.84 | PPARG (0.81) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL27955350 | 0.84 | PKM (0.72) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL24840880 | 0.84 | KMT2A (0.72) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL476215 | 0.84 | CBS (0.78) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL29435853 | 0.84 | CBS (0.78) | KMT2APKMMAPTKDM4EAPEX1 | |
| SCHEMBL28986431 | 0.84 | CBS (0.78) | KMT2APKMMAPTKDM4EAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4433077-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL Business Ltd (GB) | 2024-09-25 | — | — | EP | claimed |
| WO-2023089313-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL BUSINESS LTD (GB) | 2023-05-25 | — | — | WO | claimed |
| US-20250017950-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL BUSINESS LTD (GB) | 2025-01-16 | — | — | US | disclosed |
| EP-4433077-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL Business Ltd (GB) | 2024-09-25 | — | — | EP | disclosed |
| WO-2023089313-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | UCL BUSINESS LTD (GB) | 2023-05-25 | — | — | WO | disclosed |
| WO-2022202961-A1 | METHOD FOR PRODUCING DEMETHYLATED COMPOUND | 株式会社ダイセル | 2022-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250017950-A1 | COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS | POLRMT, TK2, GOT2 | KMT2A 565/4885PKM 536/4885MAPT 1652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.