SCHEMBL3049571

SCHEMBL3049571

[CH2]c1cnc(Cl)c(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27759683 0.77
SCHEMBL20544773 0.75
SCHEMBL19813955 0.75
SCHEMBL20544775 0.75
SCHEMBL29382049 0.72
SCHEMBL28493335 0.70 LMNA (0.45)
Water SCHEMBL27647158 0.70 TSHR (0.45)
SCHEMBL29562680 0.70 LMNA (0.45)
SCHEMBL4920941 0.70 PDXK (0.46)
SCHEMBL20544827 0.70 CHRNB2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2861566-B1 NEW DIAZASPIROCYCLOALKANE AND AZASPIROCYCLOALKANE HOFFMANN LA ROCHE (CH) 2016-12-21 EP claimed
CN-1177823-C Pesticides ��˹��ŵ�� 2004-12-01 CN claimed
US-5023259-A Pesticides, insecticides CIBA-GEIGY CORPORATION (US) 1991-06-11 US claimed
EP-0375613-A2 Nitroenamine CIBA-GEIGY AG (CH) 1990-06-27 EP claimed
EP-2999338-A1 KNOWN AND NEW HETEROCYCLIC COMPOUNDS AS PEST CONTROL AGENTS Bayer CropScience Aktiengesellschaft (DE) 2016-03-30 EP disclosed
CN-102870796-A Multi-substituted pyridyl sulfoximines and their use as insecticides DOW AGROSCIENCES LLC 2013-01-16 CN disclosed
US-8193221-B2 Insecticidal compounds SYNGENTA CROP PROTECTION LLC (US) 2012-06-05 US disclosed
WO-2012049327-A2 PESTICIDAL MIXTURES SYNGENTA PARTICIPATIONS AG (CH) 2012-04-19 WO disclosed
CN-102336748-A Substituted enaminocarbonyl compounds BAYER CROPSCIENCE AG 2012-02-01 CN disclosed
CN-101415682-B Substituted enaminocarbonyl compounds BAYER CROPSCIENCE AG (DE) 2011-12-28 CN disclosed
US-20100222392-A1 INSECTICIDAL COMPOUNDS SYNGENTA CROP PROTECTION, INC. (US) 2010-09-02 US disclosed
EP-2205574-A1 INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2010-07-14 EP disclosed
EP-0828739-B1 BICYCLIC AMINES AS INSECTICIDES SYNGENTA LTD (GB) 2002-09-11 EP disclosed
EP-1218371-A2 DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS SUNTORY LIMITED (JP) 2002-07-03 EP disclosed
WO-2001081334-A2 CYCLIC AMIDINE COMPOUNDS AND THEIR USE AS ALPHA4BETA2 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS SUNTORY LIMITED (JP) 2001-11-01 WO disclosed
WO-2001070733-A2 DI-SUBSTITUTED IMINOHETEROCYCLIC COMPOUNDS SUNTORY LIMITED (JP) 2001-09-27 WO disclosed
EP-0971918-A1 BICYCLIC AMINE DERIVATIVES ZENECA LIMITED (GB) 2000-01-19 EP disclosed
WO-1998046600-A1 BICYCLIC AMINE DERIVATIVES ZENECA LIMITED (GB) 1998-10-22 WO disclosed
US-5023259-A Pesticides, insecticides CIBA-GEIGY CORPORATION (US) 1991-06-11 US disclosed
EP-0375613-A2 Nitroenamine CIBA-GEIGY AG (CH) 1990-06-27 EP disclosed