Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20682 | 0.82 | PDE10A (0.34) | PDE10ACRHR1 | |
| SCHEMBL30497 | 0.79 | PDE10A (0.32) | PDE10ACRHR1 | |
| SCHEMBL2679823 | 0.77 | CRHR1 (0.32) | PDE10ACRHR1 | |
| SCHEMBL31283 | 0.77 | CRHR1 (0.31) | CRHR1 | |
| SCHEMBL596486 | 0.74 | ALDH1A1 (0.37) | CRHR1 | |
| SCHEMBL22064 | 0.73 | PDE10A (0.34) | PDE10ACRHR1 | |
| SCHEMBL2679434 | 0.72 | CHEK1 (0.34) | PDE10ACRHR1 | |
| SCHEMBL15026289 | 0.72 | CDK2 (0.38) | PDE10ACRHR1 | |
| SCHEMBL7885516 | 0.71 | PDE10A (0.33) | PDE10ACRHR1 | |
| SCHEMBL30714 | 0.71 | PDE10A (0.34) | PDE10ACRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2608669-A1 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-07-03 | — | — | EP | disclosed |
| WO-2012027236-A1 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS | SCHERING CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |