Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | HTR5A | P47898 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426314 | 0.84 | HTR1B (0.50) | CHKAMEN1KMT2AHTR1BHTR1A | |
| SCHEMBL30499360 | 0.82 | MEN1 (0.47) | CHKAMEN1KMT2AHTR1BPDGFRB | |
| SCHEMBL24444648 | 0.80 | PDGFRB (0.59) | PDGFRBPDGFRADRD3HRH3 | |
| SCHEMBL3896160 | 0.72 | PDGFRB (0.74) | MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL31187502 | 0.72 | PDGFRB (0.74) | MEN1KMT2APDGFRBPDGFRA | |
| SCHEMBL7246725 | 0.72 | NOS3 (0.50) | MEN1KMT2AHTR1BHTR1AHTR1D | |
| SCHEMBL4223684 | 0.70 | HRH4 (0.47) | CHKAMAPTHTR1BHTR1AHTR1D | |
| SCHEMBL13499600 | 0.69 | CHKA (0.90) | CHKAKMT2AHRH3SLC6A4 | |
| SCHEMBL28828230 | 0.68 | PDGFRB (0.53) | MEN1KMT2AMAPTPDGFRBPDGFRA | |
| SCHEMBL29616380 | 0.68 | PDGFRB (0.57) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | disclosed |