Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426314 | 0.89 | HTR1B (0.50) | MEN1KMT2ADRD3DRD2HRH3 | |
| SCHEMBL30499314 | 0.82 | CHKA (0.48) | MEN1KMT2ADRD3DRD2HRH3 | |
| SCHEMBL27007180 | 0.81 | KDM4E (0.47) | MEN1KMT2AGAAHTR1BALDH1A1 | |
| SCHEMBL30499292 | 0.81 | KDM4E (0.47) | MEN1KMT2AGAAHTR1BALDH1A1 | |
| SCHEMBL30448935 | 0.78 | PDGFRB (0.64) | ALOX15HTTALDH1A1KDM4ESRC | |
| SCHEMBL21750491 | 0.77 | KMT2A (0.75) | MEN1KMT2AGAADRD3DRD2 | |
| SCHEMBL24444648 | 0.77 | PDGFRB (0.59) | DRD3HRH3PDGFRBPDGFRA | |
| SCHEMBL27040339 | 0.75 | HTR1B (0.67) | MEN1KMT2AGAADRD3HTT | |
| SCHEMBL70306 | 0.75 | ALOX15 (0.65) | MEN1KMT2AGAAALOX15HTT | |
| SCHEMBL30905588 | 0.75 | ALOX15 (0.65) | MEN1KMT2AGAAALOX15HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | disclosed |