Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 5/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 3/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL29052474 | 1.00 | DGAT1 (0.44) | DGAT1BTKMAP4K4MAPK1DPP4 | |
| SCHEMBL29052476 | 0.83 | DGAT1 (0.42) | DGAT1BTKMAP4K4MAPK1TYRO3 | |
| SCHEMBL30499549 | 0.81 | MAP4K4 (0.49) | MAP4K4TYRO3MERTKAXLPIK3CD | |
| SCHEMBL29052482 | 0.81 | MAP4K4 (0.49) | MAP4K4TYRO3MERTKAXLPIK3CD | |
| SCHEMBL30367384 | 0.75 | MAPK1 (0.40) | DGAT1MAP4K4MAPK1TYRO3MERTK | |
| SCHEMBL30367356 | 0.75 | DGAT1 (0.42) | DGAT1MAPK1PIK3CD | |
| SCHEMBL30367399 | 0.74 | TLR9 (0.42) | DGAT1BTKMAPK1 | |
| SCHEMBL30367296 | 0.74 | MAPK1 (0.39) | DGAT1BTKMAPK1TYRO3MERTK | |
| SCHEMBL29720981 | 0.71 | SRC (0.58) | BTKEGFR | |
| SCHEMBL28344421 | 0.71 | SRC (0.58) | BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |