Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 6/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | FLT3 | P36888 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | BLK | P51451 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367384 | 0.80 | MAPK1 (0.40) | DGAT1KITKDRFLT3SMN1; SMN2 | |
| SCHEMBL30367399 | 0.79 | TLR9 (0.42) | DGAT1MAPK1TLR9TLR8TLR7 | |
| SCHEMBL30367296 | 0.79 | MAPK1 (0.39) | DGAT1SMN1; SMN2MAPK1TLR9TLR8 | |
| Trifluoroacetic Acid SCHEMBL30367156 | 0.75 | DGAT1 (0.44) | DGAT1MAPK1PIK3CD | |
| Trifluoroacetic Acid SCHEMBL29052474 | 0.75 | DGAT1 (0.44) | DGAT1MAPK1PIK3CD | |
| SCHEMBL30367699 | 0.73 | KDM1A (0.41) | DGAT1MAPK1TLR9TLR8NAMPT | |
| SCHEMBL30367527 | 0.72 | MERTK (0.38) | KITSMN1; SMN2ALDH1A1MAPK1TLR9 | |
| SCHEMBL30367097 | 0.72 | BTK (0.44) | SMN1; SMN2TLR9TLR8 | |
| SCHEMBL30367867 | 0.70 | KDM4E (0.40) | ALDH1A1MAPK1TLR9TLR8NAMPT | |
| SCHEMBL30367001 | 0.69 | DGAT1 (0.39) | DGAT1SMN1; SMN2ALDH1A1MAPK1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |