Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22290184 | 1.00 | SLC6A4 (0.59) | SLC6A4SLC6A3L3MBTL1MKNK1MKNK2 | |
| SCHEMBL698991 | 0.86 | L3MBTL1 (0.55) | L3MBTL1ACLYPTGS1SMN1; SMN2KDM4E | |
| SCHEMBL5517057 | 0.85 | SLC6A3 (0.59) | SLC6A4SLC6A3L3MBTL1MKNK1MKNK2 | |
| SCHEMBL9301522 | 0.85 | SLC6A3 (0.57) | SLC6A4SLC6A3L3MBTL1MKNK1MKNK2 | |
| SCHEMBL28865711 | 0.85 | L3MBTL1 (0.51) | SLC6A4SLC6A3L3MBTL1MKNK1MKNK2 | |
| SCHEMBL28825335 | 0.84 | KLRK1 (0.52) | L3MBTL1METAP2 | |
| SCHEMBL28250388 | 0.84 | L3MBTL1 (0.50) | SLC6A4SLC6A3L3MBTL1MKNK1MKNK2 | |
| SCHEMBL69177 | 0.84 | L3MBTL1 (0.64) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL4700610 | 0.82 | L3MBTL1 (0.49) | SLC6A4SLC6A3L3MBTL1MKNK1MKNK2 | |
| SCHEMBL28972835 | 0.82 | MKNK1 (0.46) | SLC6A4SLC6A3L3MBTL1MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |