Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL698991 | 0.86 | L3MBTL1 (0.55) | L3MBTL1PRKCZACLYKMT2AHTT | |
| SCHEMBL30499558 | 0.85 | SLC6A4 (0.59) | SLC6A3L3MBTL1MKNK1MKNK2METAP2 | |
| SCHEMBL22290184 | 0.85 | SLC6A4 (0.59) | SLC6A3L3MBTL1MKNK1MKNK2METAP2 | |
| SCHEMBL5517057 | 0.85 | SLC6A3 (0.59) | SLC6A3L3MBTL1MAPTTLR7MKNK1 | |
| SCHEMBL28865711 | 0.85 | L3MBTL1 (0.51) | SLC6A3L3MBTL1MKNK1MKNK2METAP2 | |
| SCHEMBL28250388 | 0.84 | L3MBTL1 (0.50) | SLC6A3L3MBTL1MKNK1MKNK2METAP2 | |
| SCHEMBL69177 | 0.84 | L3MBTL1 (0.64) | L3MBTL1MAPTMAP2K1ALOX15HTT | |
| SCHEMBL4700610 | 0.82 | L3MBTL1 (0.49) | SLC6A3L3MBTL1MAPTMKNK1MKNK2 | |
| SCHEMBL28908478 | 0.82 | TLR7 (0.46) | SLC6A3L3MBTL1MAPTTLR7MKNK1 | |
| SCHEMBL28825335 | 0.81 | KLRK1 (0.52) | L3MBTL1MAPTTLR7METAP2TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009002-A1 | 2-(AZA-9-FLUORENONYL)CARBAPENEM ANTIBACTERIAL AGENTS | MERCK & CO., INC. (US) | 1994-04-28 | — | — | WO | disclosed |
| US-5294610-A | Staphylococcus; side effect reduction | MERCK & CO. INC. (US) | 1994-03-15 | — | — | US | disclosed |