SCHEMBL30499673

SCHEMBL30499673

Cc1ccc(Cl)c(NC(N)=O)c1Cl

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.65
LMNA P02545 2/20 0.65
CLCN2 P51788 5/20 0.55
PTGS2 P35354 5/20 0.49
MEN1 O00255 2/20 0.49
MAPK1 P28482 2/20 0.49
KMT2A Q03164 2/20 0.49
METTL3 Q86U44 2/20 0.49
AKR1B10 O60218 1/20 0.49
ABCB11 O95342 1/20 0.49
TTR P02766 1/20 0.49
ADORA3 P0DMS8 1/20 0.49
CHRM1 P11229 1/20 0.49
FABP2 P12104 1/20 0.49
RXRA P19793 1/20 0.49
TBXA2R P21731 1/20 0.49
NR4A1 P22736 1/20 0.49
PTGS1 P23219 1/20 0.49
PDE4A P27815 1/20 0.49
AKR1C3 P42330 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7760768 1.00 ALDH1A1 (0.65) ALDH1A1LMNACLCN2PTGS2MEN1
SCHEMBL5155916 0.84 NPC1 (0.47) ALDH1A1LMNACLCN2MEN1KMT2A
SCHEMBL8130619 0.83 ALDH1A1 (0.67) ALDH1A1LMNACLCN2PTGS2MEN1
SCHEMBL11175677 0.79 ALDH1A1 (0.41) ALDH1A1LMNACLCN2PTGS2MEN1
SCHEMBL8682011 0.78 GAA (0.60) ALDH1A1PTGS2GAACXCL8
SCHEMBL11842930 0.76 ALDH1A1 (0.50) ALDH1A1LMNACLCN2PTGS2MEN1
SCHEMBL28784403 0.74 CLCN2 (0.44) ALDH1A1LMNACLCN2PTGS2MEN1
SCHEMBL1439894 0.74 TYK2 (0.52) LMNAMEN1KMT2ACYP1A2GAA
Hydrochloric Acid SCHEMBL15110990 0.72 LMNA (0.49) ALDH1A1LMNACLCN2PTGS2MEN1
SCHEMBL9264265 0.72 CLCN2 (1.00) LMNACLCN2PTGS2MEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed