Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.41 |
| ▸ | GCGR | P47871 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568795 | 0.85 | CYP11B2 (0.61) | CYP11B2MMP3KIF11GSK3AGSK3B | |
| SCHEMBL13063634 | 0.85 | CYP11B2 (0.61) | CYP11B2MMP3KIF11GSK3AGSK3B | |
| SCHEMBL30358109 | 0.78 | MAPT (0.65) | KIF11GAANOTUMLMNAMAPT | |
| Water SCHEMBL11055485 | 0.75 | MMP3 (0.74) | CYP11B2MMP3KIF11CA12CA1 | |
| SCHEMBL26246 | 0.75 | MMP3 (0.74) | CYP11B2MMP3KIF11CA12CA1 | |
| SCHEMBL396846 | 0.75 | MMP3 (0.74) | CYP11B2MMP3KIF11CA12CA1 | |
| SCHEMBL13063633 | 0.75 | MMP3 (0.74) | CYP11B2MMP3KIF11CA12CA1 | |
| SCHEMBL15159900 | 0.74 | LRRK2 (0.60) | CYP11B2MMP3KIF11GSK3AGSK3B | |
| SCHEMBL25543310 | 0.74 | CYP11B2 (0.50) | CYP11B2MMP3KIF11GSK3AGSK3B | |
| SCHEMBL25543818 | 0.74 | CYP11B2 (0.50) | CYP11B2MMP3KIF11GSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909133-B | Substituted 1-amino-1H-imidazole-5-carboxamides as inhibitors of brunauer tyrosine kinase | 河南知微生物医药有限公司 | 2023-07-14 | — | — | CN | disclosed |