SCHEMBL13063634

SCHEMBL13063634

N#Cc1ccc(-c2ccc(-c3ccc(-c4ccncc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP11B2 P19099 2/20 0.61
▸ MMP3 P08254 1/20 0.56
▸ KIF11 P52732 2/20 0.56
▸ LMNA P02545 1/20 0.55
▸ MAPT P10636 1/20 0.55
▸ GSK3A P49840 2/20 0.51
▸ GSK3B P49841 2/20 0.51
▸ MAPK14 Q16539 3/20 0.50
▸ MAPK13 O15264 2/20 0.50
▸ MAPK12 P53778 2/20 0.50
▸ MAPK11 Q15759 2/20 0.50
▸ RAF1 P04049 1/20 0.50
▸ GCGR P47871 2/20 0.49
▸ ALOX5 P09917 1/20 0.49
▸ CYP11B1 P15538 1/20 0.49
▸ CCNC P24863 1/20 0.48
▸ CDK8 P49336 1/20 0.48
▸ PKN1 Q16512 1/20 0.47
▸ PKN2 Q16513 1/20 0.47
▸ CA12 O43570 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2568795 1.00 CYP11B2 (0.61) CYP11B2MMP3KIF11LMNAMAPT
SCHEMBL25543310 0.88 CYP11B2 (0.50) CYP11B2MMP3KIF11LMNAMAPT
SCHEMBL25543818 0.88 CYP11B2 (0.50) CYP11B2MMP3KIF11LMNAMAPT
SCHEMBL15159900 0.88 LRRK2 (0.60) CYP11B2MMP3KIF11GSK3AGSK3B
SCHEMBL30500119 0.85 CYP11B2 (0.52) CYP11B2MMP3KIF11LMNAMAPT
Isonicotinonitrile SCHEMBL151611 0.84 — —
Isonicotinonitrile SCHEMBL2015834 0.84 HDAC8 (0.52) CYP11B2KIF11LMNAMAPTCYP11B1
Isonicotinonitrile SCHEMBL12264099 0.84 — —
Water SCHEMBL11055485 0.84 MMP3 (0.74) CYP11B2MMP3KIF11CA12CA1
SCHEMBL396846 0.84 MMP3 (0.74) CYP11B2MMP3KIF11CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905260-B2 Method for manufacturing optical information recording medium FUJIFILM CORPORATION (JP) 2018-02-27 — — US disclosed
US-9711176-B2 Multilayer optical information recording disk and method for manufacturing same FUJIFILM CORPORATION (JP) 2017-07-18 — — US disclosed
US-9514779-B2 Method for manufacturing multilayer structure sheet, and optical information recording medium FUJIFILM CORPORATION (JP) 2016-12-06 — — US disclosed
US-20150364153-A1 METHOD FOR MANUFACTURING OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2015-12-17 — — US disclosed
US-20150318013-A1 MULTILAYER OPTICAL INFORMATION RECORDING DISK AND METHOD FOR MANUFACTURING SAME FUJIFILM CORPORATION (JP) 2015-11-05 — — US disclosed
US-8980396-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2015-03-17 — — US disclosed
US-8953427-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2015-02-10 — — US disclosed
US-20140193601-A1 METHOD FOR MANUFACTURING MULTILAYER STRUCTURE SHEET, AND OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-07-10 — — US disclosed
US-20140153375-A1 OPTICAL INFORMATION RECORDING MEDIUM, METHOD FOR MANUFACTURING SAME AND RECORDING METHOD FOR OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-06-05 — — US disclosed
US-8670296-B2 Optical information recording medium and optical information recording method FUJIFILM CORPORATION (JP) 2014-03-11 — — US disclosed
US-20140023816-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2014-01-23 — — US disclosed
US-20130229901-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-09-05 — — US disclosed
US-8526291-B2 Optical information recording medium FUJIFILM CORPORATION (JP) 2013-09-03 — — US disclosed
US-20130128710-A1 OPTICAL INFORMATION RECORDING MEDIUM FUJIFILM CORPORATION (JP) 2013-05-23 — — US disclosed
US-20130100791-A1 OPTICAL INFORMATION RECORDING MEDIUM AND OPTICAL INFORMATION RECORDING METHOD FUJIFILM CORPORATION (JP) 2013-04-25 — — US disclosed
US-20100330496-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING-REPRODUCTION METHOD, AND SIMULTANEOUS TWO-PHOTON ABSORPTION RECORDING MATERIAL FOR USE THEREIN FUJIFILM CORPORATION (JP) 2010-12-30 — — US disclosed
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND FUJIFILM CORPORATION (JP) 2010-04-01 — — US disclosed
US-20090246443-A1 SIMULTANEOUS TWO-PHOTON ABSORPTION THREE-DIMENSIONAL OPTICAL RECORDING MEDIUM AND SIMULTANEOUS TWO-PHOTON THREE-DIMENSIONAL OPTICAL RECORDING METHOD FUJIFILM CORPORATION (JP) 2009-10-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100078607-A1 NON-RESONANT TWO-PHOTON ABSORPTION RECORDING MATERIAL AND NON-RESONANT TWO-PHOTON ABSORPTION COMPOUND SIGMAR1, SFN, CRY2 CYP11B2 2464/4885MMP3 2936/4885KIF11 4606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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