Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3723576 | 0.99 | UCHL1 (0.42) | UCHL1USP30ALDH1A1GPR119TSHR | |
| SCHEMBL15773304 | 0.99 | UCHL1 (0.42) | UCHL1USP30ALDH1A1GPR119TSHR | |
| SCHEMBL34474164 | 0.95 | ALDH1A1 (0.46) | UCHL1USP30ALDH1A1GPR119TSHR | |
| SCHEMBL47019 | 0.95 | ALDH1A1 (0.46) | UCHL1USP30ALDH1A1GPR119TSHR | |
| SCHEMBL239739 | 0.95 | ALDH1A1 (0.46) | UCHL1USP30ALDH1A1GPR119TSHR | |
| SCHEMBL28341942 | 0.83 | HTR2B (0.40) | UCHL1USP30ALDH1A1GPR119KDM4E | |
| SCHEMBL12295053 | 0.81 | UCHL1 (0.36) | UCHL1USP30ALDH1A1GPR119KMT2A | |
| SCHEMBL29587469 | 0.80 | UCHL1 (0.41) | UCHL1USP30ALDH1A1TSHRKMT2A | |
| SCHEMBL25591844 | 0.80 | RIPK1 (0.53) | UCHL1USP30LMNA | |
| SCHEMBL29533798 | 0.79 | L3MBTL1 (0.37) | ALDH1A1KMT2AMEN1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909133-B | Substituted 1-amino-1H-imidazole-5-carboxamides as inhibitors of brunauer tyrosine kinase | 河南知微生物医药有限公司 | 2023-07-14 | — | — | CN | disclosed |