Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974555 | 1.00 | ALOX15 (0.59) | ALOX15MAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL30503031 | 0.90 | ALOX15 (0.50) | ALOX15MAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL13019728 | 0.86 | SMN1; SMN2 (0.48) | ALOX15MAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL13817788 | 0.85 | ALDH1A1 (0.44) | ALOX15MAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL11775529 | 0.85 | GSK3B (0.65) | ALOX15MAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL19619634 | 0.83 | NPC1 (0.50) | ALOX15MAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL29046810 | 0.82 | ALDH1A1 (0.41) | ALOX15MAPK1TDP1HSD17B10ALDH1A1 | |
| SCHEMBL20076975 | 0.81 | ELANE (0.60) | MAPK1TDP1ALDH1A1LMNARAB9A | |
| SCHEMBL2733809 | 0.80 | CA1 (0.64) | TDP1ALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL322440 | 0.79 | CA1 (0.59) | MAPK1HSD17B10ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024168936-A1 | β-DIKETONE MULTI-ELEMENT RARE EARTH COMPLEX, PREPARATION METHOD THEREFOR, AND USE THEREOF | 包头稀土研究院 | 2024-08-22 | — | — | WO | disclosed |
| CN-116332968-A | Beta-diketone polynary rare earth complex and preparation method and application thereof | 包头稀土研究院 | 2023-06-27 | — | — | CN | disclosed |