Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.34 |
| ▸ | TTR | P02766 | 3/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503585 | 0.88 | TTR (0.34) | TTRRBP4FAAH | |
| SCHEMBL25409272 | 0.84 | LOXL2 (0.41) | LOXL2TTRRBP4ABHD6MGLL | |
| SCHEMBL26631358 | 0.80 | GPR119 (0.46) | LOXL2ABHD6MGLL | |
| SCHEMBL25412517 | 0.80 | P2RX3 (0.32) | LOXL2 | |
| SCHEMBL26739231 | 0.79 | LOXL2 (0.38) | LOXL2TTRABHD6MGLLFAAH | |
| SCHEMBL26631210 | 0.79 | LOXL2 (0.38) | LOXL2TTRABHD6MGLLFAAH | |
| SCHEMBL31171162 | 0.77 | GPR119 (0.43) | LOXL2ABHD6MGLL | |
| SCHEMBL26748896 | 0.76 | LOXL2 (0.38) | LOXL2ABHD6MGLLFFAR1 | |
| SCHEMBL30503598 | 0.76 | MGLL (0.32) | MGLL | |
| SCHEMBL31171112 | 0.75 | NR1H2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217062-B1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-09 | — | — | EP | disclosed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |