Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.31 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.30 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | XPO1 | O14980 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815372 | 1.00 | NOTUM (0.43) | NOTUMTACR1ACP1SLC6A4S1PR1 | |
| SCHEMBL7694014 | 0.84 | TACR1 (0.43) | TACR1S1PR1P2RX1TSHRAURKA | |
| SCHEMBL1410175 | 0.78 | NOTUM (0.47) | NOTUMTACR1ACP1TAS2R14P2RX1 | |
| SCHEMBL1409680 | 0.78 | NOTUM (0.41) | NOTUMTACR1ACP1TAS2R14P2RX1 | |
| SCHEMBL12436182 | 0.77 | NOTUM (0.46) | NOTUMTACR1ACP1TAS2R14P2RX1 | |
| SCHEMBL14092975 | 0.77 | GABRA1 (0.39) | TACR1P2RX1TSHRAURKACES2 | |
| SCHEMBL14228532 | 0.77 | RAPGEF4 (0.40) | NOTUMTACR1TAS2R14P2RX1GPBAR1 | |
| SCHEMBL1082212 | 0.77 | NOTUM (0.50) | NOTUMACP1S1PR1S1PR3TAS2R14 | |
| SCHEMBL21201333 | 0.77 | ALDH1A1 (0.42) | TSHRAURKA | |
| SCHEMBL131138 | 0.77 | NOTUM (0.50) | NOTUMACP1S1PR1S1PR3TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |