Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14092975 | 0.91 | GABRA1 (0.39) | TACR1CES2P2RX1TSHRIDO1 | |
| SCHEMBL14228532 | 0.86 | RAPGEF4 (0.40) | TACR1P2RX1TSHRMAPTRAPGEF4 | |
| SCHEMBL6815372 | 0.84 | NOTUM (0.43) | TACR1CES2P2RX1TSHRSLC2A1 | |
| SCHEMBL5114612 | 0.84 | MAPK1 (0.42) | TACR1P2RX1TSHRIDO1MAPT | |
| SCHEMBL30503556 | 0.84 | NOTUM (0.43) | TACR1CES2P2RX1TSHRSLC2A1 | |
| SCHEMBL11907625 | 0.84 | P2RX1 (0.42) | TACR1P2RX1TSHRRAPGEF4ALDH1A1 | |
| SCHEMBL15934222 | 0.84 | ALDH1A1 (0.42) | TACR1CES2P2RX1TSHRALDH1A1 | |
| SCHEMBL27650523 | 0.84 | TACR1 (0.35) | TACR1CES2P2RX1TSHRSLC2A1 | |
| SCHEMBL657091 | 0.84 | TACR1 (0.43) | TACR1CES2P2RX1IDO1MAPT | |
| SCHEMBL14117328 | 0.81 | SIGMAR1 (0.40) | TACR1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912822-B2 | Process of manufacturing polyols | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-02-27 | — | — | US | disclosed |
| US-20200354383-A1 | PROCESS OF MANUFACTURING POLYOLS | DOW GLOBAL TECHNOLOGIES LLC | 2020-11-12 | — | — | US | disclosed |
| WO-2019055727-A1 | PROCESS OF MANUFACTURING POLYOLS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-21 | — | — | WO | disclosed |
| WO-2019055742-A1 | PROCESS OF MANUFACTURING SURFACTANTS AND LUBRICANTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2019-03-21 | — | — | WO | disclosed |
| EP-3036236-B1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | LEO PHARMA AS (DK) | 2017-06-07 | — | — | EP | disclosed |
| US-20160207930-A1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | LEO PHARMA A/S (DK) | 2016-07-21 | — | — | US | disclosed |
| EP-3036236-A1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | LEO PHARMA A/S (DK) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015024878-A1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | LEO PHARMA A/S (DK) | 2015-02-26 | — | — | WO | disclosed |
| WO-2015024203-A1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | LEO PHARMA A/S (DK) | 2015-02-26 | — | — | WO | disclosed |
| US-6337297-B1 | CHROMIUM CATALYST FOR TRIMERIZATION OF ETHYLENE WITH MULTIDENTATE LIGAND OR HALOGEN, CARBOXY GROUP | TOSOH CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11912822-B2 | Process of manufacturing polyols | MRPL21, RER1, PCBP1 | TACR1 2730/4885CES2 906/4885P2RX1 2102/4885 |
| US-20200354383-A1 | PROCESS OF MANUFACTURING POLYOLS | MRPL21, RER1, PCBP1 | TACR1 2730/4885CES2 906/4885P2RX1 2102/4885 |
| US-20160207930-A1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | TACR2, TACR1, HRH4 | TACR1 2/4885CES2 2503/4885P2RX1 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.