⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29497376 | 0.82 | — | — | |
| SCHEMBL25410957 | 0.81 | FFAR4 (0.31) | — | |
| SCHEMBL29427075 | 0.79 | — | — | |
| SCHEMBL25410315 | 0.79 | — | — | |
| SCHEMBL29426971 | 0.76 | GPR119 (0.40) | — | |
| SCHEMBL26631457 | 0.76 | GPR119 (0.40) | — | |
| SCHEMBL29497354 | 0.73 | TDO2 (0.35) | — | |
| SCHEMBL25413735 | 0.72 | ACACB (0.31) | — | |
| SCHEMBL25410707 | 0.70 | — | — | |
| SCHEMBL29497455 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |