SCHEMBL3050480

SCHEMBL3050480

CC(CN)c1ccc(-n2cccc(CCO)c2=O)cc1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.38
F2 P00734 3/20 0.33
F10 P00742 3/20 0.33
MAPT P10636 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
PBK Q96KB5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14924770 0.72 F2 (0.38) F2F10MAPT
SCHEMBL2591544 0.72 TSHR (0.47) MAPTMEN1KMT2A
SCHEMBL31618496 0.66 TRIM24 (0.39) TAAR1MAPTMEN1KMT2A
SCHEMBL16794677 0.65 ALDH1A1 (0.37) MAPTMEN1KMT2A
SCHEMBL14924782 0.65 COMT (0.46) F2F10MAPT
SCHEMBL13153503 0.64 FAAH (0.35) MAPT
SCHEMBL15229026 0.64 BIRC5 (0.53) TAAR1MAPT
SCHEMBL2471740 0.64 F2 (0.39) F2F10
SCHEMBL2471712 0.64 RAB9A (0.38) F2F10MAPTMEN1KMT2A
SCHEMBL3006604 0.64 TAAR1 (0.75) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8487111-B2 Substituted oxazolidinones and their use BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-16 US disclosed
US-20100261759-A1 SUBSTITUTED OXAZOLIDINONES AND THEIR USE BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100261759-A1 SUBSTITUTED OXAZOLIDINONES AND THEIR USE XDH, MPL, OXA1L TAAR1 4803/4885F2 30/4885F10 360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.