Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10625562 | 0.83 | KEAP1 (0.46) | KEAP1PLA2G7KMT2ASMN1; SMN2GAA | |
| SCHEMBL28873592 | 0.78 | ERN1 (0.52) | ERN1KMT2ANFE2L2LMNAMEN1 | |
| SCHEMBL10270717 | 0.77 | KEAP1 (0.52) | KEAP1PLA2G7KMT2ASMN1; SMN2GAA | |
| SCHEMBL3821879 | 0.76 | ERN1 (0.53) | ERN1KMT2ASMN1; SMN2NFE2L2LMNA | |
| SCHEMBL4684231 | 0.75 | KEAP1 (0.39) | PTGES2KEAP1PLA2G7KMT2ASMN1; SMN2 | |
| SCHEMBL17553989 | 0.74 | PSIP1 (0.43) | KEAP1PLA2G7KMT2ASMN1; SMN2GAA | |
| SCHEMBL27688702 | 0.72 | KIF11 (0.48) | PTGES2KEAP1PLA2G7CYP2C19KMT2A | |
| SCHEMBL2737238 | 0.72 | L3MBTL1 (0.54) | KMT2ASMN1; SMN2LMNAMEN1KDM4E | |
| SCHEMBL221303 | 0.71 | ALB (0.49) | KEAP1PLA2G7KMT2AGAAALDH1A1 | |
| SCHEMBL31046903 | 0.71 | ALB (0.49) | KEAP1PLA2G7KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116675635-B | Method for synthesizing 3-vinyl indole-2-ketone derivative with high stereoselectivity | 常州大学 | 2025-06-24 | — | — | CN | disclosed |
| CN-116675635-A | Method for synthesizing 3-vinyl indole-2-ketone derivative with high stereoselectivity | 常州大学 | 2023-09-01 | — | — | CN | disclosed |