Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28572920 | 1.00 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAALDH1A1KMT2AMKNK1 | |
| SCHEMBL20465066 | 0.81 | NOTUM (0.51) | SMN1; SMN2ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL17858741 | 0.80 | NPC1 (0.49) | SMN1; SMN2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL1662946 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNAALDH1A1KMT2AMKNK1 | |
| SCHEMBL330565 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2LMNAALDH1A1KMT2AMKNK1 | |
| SCHEMBL24897238 | 0.79 | RAB9A (0.56) | SMN1; SMN2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL6960706 | 0.79 | ALDH1A1 (0.66) | SMN1; SMN2LMNAALDH1A1KMT2AMKNK1 | |
| SCHEMBL6967479 | 0.79 | MKNK1 (0.66) | SMN1; SMN2LMNAALDH1A1KMT2AMKNK1 | |
| SCHEMBL17279800 | 0.79 | RAB9A (0.56) | SMN1; SMN2ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL1853364 | 0.79 | LMNA (0.56) | SMN1; SMN2LMNAALDH1A1KMT2AMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876482-B | Polysubstituted heterocyclic derivative, preparation method and medical application thereof | 中国药科大学 | 2023-07-28 | — | — | CN | disclosed |