SCHEMBL330565

SCHEMBL330565

Nc1cc(-c2ccccc2)[nH]n1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
KMT2A Q03164 3/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
MEN1 O00255 2/20 0.66
MKNK1 Q9BUB5 1/20 0.66
MKNK2 Q9HBH9 1/20 0.66
USP2 O75604 1/20 0.66
RAB9A P51151 2/20 0.61
POLB P06746 1/20 0.61
MITF O75030 1/20 0.59
TP53 P04637 1/20 0.59
DYRK1A Q13627 1/20 0.59
MAPT P10636 2/20 0.56
NPC1 O15118 1/20 0.56
GFER P55789 1/20 0.56
LMNA P02545 2/20 0.56
LTA4H P09960 1/20 0.54
KDM4E B2RXH2 2/20 0.53
GAA P10253 1/20 0.53
STAT1 P42224 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6956022 0.96 ALDH1A1 (0.67) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL5725231 0.86 RAB9A (0.66) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL14190747 0.84 LTA4H (0.74) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL28573902 0.83 ALDH1A1 (0.71) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL1852281 0.81 ALDH1A1 (0.63) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL1702207 0.79 ALDH1A1 (0.67) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL5630086 0.79 MKNK1 (1.00) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL1662946 0.79 SMN1; SMN2 (1.00) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL2303414 0.79 ALDH1A1 (0.67) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1
SCHEMBL13815700 0.79 KMT2A (1.00) ALDH1A1KMT2ASMN1; SMN2MEN1MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 698 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535356-A 3-amino-5-phenyl-pyrazole derivative tubulin inhibitor and preparation and medical application thereof 中国药科大学 2023-08-04 CN claimed
US-9486892-B2 Polishing composition FUJIMI INCORPORATED (JP) 2016-11-08 US claimed
CN-102161879-B Polishing composition and polishing method using the same FUJIMI INC 2015-02-25 CN claimed
US-8703007-B2 Polishing composition and polishing method using the same FUJIMI INCORPORATED (JP) 2014-04-22 US claimed
EP-2228065-B1 Heterocyclo inhibitors of potassium channel function BRISTOL MYERS SQUIBB CO (US) 2012-12-26 EP claimed
CN-1665801-B Anti tubercular drug: compositions and methods DEPT OF HEALTH AND HUMAN SERVI 2011-05-11 CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-6106599-A Inks XEROX CORPORATION (US) 2000-08-22 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
CN-116535356-B 3-Amino-5-phenyl-pyrazole derivative tubulin inhibitor and preparation and medical application thereof 中国药科大学 2026-03-17 CN disclosed
CN-116535356-B 3-Amino-5-phenyl-pyrazole derivative tubulin inhibitor and preparation and medical application thereof 中国药科大学 2026-03-17 CN disclosed
US-12545649-B2 WDR5-MYC inhibitors VANDERBILT UNIVERSITY (US) 2026-02-10 US disclosed
US-4456668-A DYE BLEACH, TEXTILE DYES CIBA GEIGY AG (CH) 1984-06-26 US disclosed
US-4409143-A TEXTILES, PHOTOGRAPHY CIBA-GEIGY AG (CH) 1983-10-11 US disclosed
US-4218369-A FOR DYEING POLYACRYLONITRILE PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1980-08-19 US disclosed
US-4043751-A BENZENE OR NAPHTHALENE NUCLEUS PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1977-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12545649-B2 WDR5-MYC inhibitors MYC, MYCBP, WDR1 ALDH1A1 4135/4885KMT2A 1056/4885SMN1; SMN2 3142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.