Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Flomoxef. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 18/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flomoxef SCHEMBL49438 | 0.82 | PTGS1 (0.57) | PTGS1HSD17B10TDP1CMA1 | |
| Flomoxef SCHEMBL14423926 | 0.82 | PTGS1 (0.57) | PTGS1HSD17B10TDP1CMA1 | |
| Flomoxef SCHEMBL65125 | 0.82 | PTGS1 (0.57) | PTGS1HSD17B10TDP1CMA1 | |
| Flomoxef SCHEMBL30531854 | 0.80 | HSD17B10 (0.58) | PTGS1HSD17B10TDP1CMA1 | |
| Flomoxef SCHEMBL30716855 | 0.80 | HSD17B10 (0.58) | PTGS1HSD17B10TDP1CMA1 | |
| Moxalactam SCHEMBL29352102 | 0.74 | PTGS1 (0.64) | PTGS1HSD17B10TDP1CMA1 | |
| SCHEMBL29727496 | 0.71 | ELANE (0.44) | PTGS1HSD17B10TDP1CMA1 | |
| SCHEMBL29501762 | 0.71 | ELANE (0.43) | PTGS1HSD17B10TDP1CMA1 | |
| SCHEMBL30515648 | 0.70 | CMA1 (0.60) | PTGS1CMA1 | |
| SCHEMBL29449939 | 0.69 | HSD17B10 (0.43) | PTGS1HSD17B10TDP1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119688881-A | Method for analyzing related substances of flomoxef sodium | 广州艾奇西医药科技有限公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-116514841-A | Preparation method of flomoxef acid impurity | 福建省福抗药业股份有限公司 | 2023-08-01 | — | — | CN | disclosed |