Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Flomoxef. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | CMA1 | P23946 | 18/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flomoxef SCHEMBL49438 | 0.99 | PTGS1 (0.57) | PTGS1CMA1HSD17B10TDP1 | |
| Flomoxef SCHEMBL14423926 | 0.99 | PTGS1 (0.57) | PTGS1CMA1HSD17B10TDP1 | |
| Flomoxef SCHEMBL27661462 | 0.99 | PTGS1 (0.57) | PTGS1CMA1HSD17B10TDP1 | |
| Flomoxef SCHEMBL30531854 | 0.92 | HSD17B10 (0.58) | PTGS1CMA1HSD17B10TDP1 | |
| Flomoxef SCHEMBL30716855 | 0.92 | HSD17B10 (0.58) | PTGS1CMA1HSD17B10TDP1 | |
| Flomoxef SCHEMBL27896310 | 0.92 | PTGS1 (0.51) | PTGS1CMA1HSD17B10TDP1 | |
| SCHEMBL30515648 | 0.85 | CMA1 (0.60) | PTGS1CMA1 | |
| Flomoxef SCHEMBL30515667 | 0.82 | PTGS1 (0.44) | PTGS1CMA1HSD17B10TDP1 | |
| Flomoxef SCHEMBL5490277 | 0.78 | ABCB11 (0.52) | PTGS1CMA1TDP1 | |
| Flomoxef SCHEMBL18065040 | 0.78 | NR1I2 (0.58) | PTGS1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 404 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120131570-A | Freeze-dried preparation of flomoxef sodium for injection and preparation method | 四川制药制剂有限公司 | 2025-06-13 | — | — | CN | claimed |
| US-12274830-B2 | Nitric oxide inhalation therapy for infants with bronchiolitis | BEYOND AIR LTD (IL) | 2025-04-15 | — | — | US | claimed |
| CN-119688881-A | Method for analyzing related substances of flomoxef sodium | 广州艾奇西医药科技有限公司 | 2025-03-25 | — | — | CN | claimed |
| US-20240173512-A1 | METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS | STREETERVILLE CAPITAL, LLC | 2024-05-30 | — | — | US | claimed |
| US-11890421-B2 | Methods for potentiating antimicrobial agents | BEYOND AIR LTD (IL) | 2024-02-06 | — | — | US | claimed |
| CN-115382410-B | Device for preparing flomoxef sodium for injection and preparation method | 成都晶富医药科技有限公司 | 2024-01-23 | — | — | CN | claimed |
| CN-116589483-A | Preparation method of high-purity flomoxef sodium for injection | 四川制药制剂有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-115382410-A | Flomoxef sodium blending device for injection and preparation method | 成都晶富医药科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-111187285-B | Crystal form of flomoxef sodium, preparation method, pharmaceutical composition and application | 泊诺(天津)创新医药研究有限公司 | 2022-09-30 | — | — | CN | claimed |
| US-11376194-B2 | Infusion system | OH PHARMACEUTICAL CO., LTD. (US) | 2022-07-05 | — | — | US | claimed |
| US-20100239690-A1 | COMPOSITION FOR ORAL CAVITY AND SKIN | NODA SATOSHI | 2010-09-23 | — | — | US | claimed |
| EP-2136844-A1 | COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF | Centre De Recherche Sur Les Biotechnologies Marine (CA) | 2009-12-30 | — | — | EP | claimed |
| WO-2009131692-A1 | SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2009-10-29 | — | — | WO | claimed |
| WO-2008113177-A1 | COMPOSITIONS COMPRISING POLYUNSATURATED FATTY ACID MONOGLYCERIDES OR DERIVATIVES THEREOF AND USES THEREOF | CENTRE DE RECHERCHE SUR LES BIOTECHNOLOGIES MARINES (CA) | 2008-09-25 | — | — | WO | claimed |
| CN-100350977-C | Pharmaceutical composition | OTSUKA PHARMA CO LTD (JP) | 2007-11-28 | — | — | CN | claimed |
| CN-1813699-A | Medicinal composition | OTSUKA PHARMA CO LTD (JP) | 2006-08-09 | — | — | CN | claimed |
| CN-1518461-A | Pharmaceutical composition | 大V制药株式会社 | 2004-08-04 | — | — | CN | claimed |
| US-6406717-B2 | Rapid-melt semi-solid compositions, methods of making same and methods of using same | CAPRICORN PHARMA, INC. | 2002-06-18 | — | — | US | claimed |
| US-20020004071-A1 | Rapid-melt semi-solid compositions, methods of making same and methods of using same | CAPRICORN PHARMA, INC. | 2002-01-10 | — | — | US | claimed |
| WO-2002002080-A1 | RAPID-MELT SEMI-SOLID COMPOSITIONS, METHODS OF MAKING SAME AND METHODS OF USING SAME | CAPRICORN PHARMA, INC. (US) | 2002-01-10 | — | — | WO | claimed |