Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Flomoxef. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CMA1 | P23946 | 15/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Flomoxef SCHEMBL30716855 | 1.00 | HSD17B10 (0.58) | HSD17B10TDP1CMA1PTGS1BLM | |
| Flomoxef SCHEMBL49438 | 0.93 | PTGS1 (0.57) | HSD17B10TDP1CMA1PTGS1 | |
| Flomoxef SCHEMBL14423926 | 0.93 | PTGS1 (0.57) | HSD17B10TDP1CMA1PTGS1 | |
| Flomoxef SCHEMBL65125 | 0.92 | PTGS1 (0.57) | HSD17B10TDP1CMA1PTGS1 | |
| Flomoxef SCHEMBL27661462 | 0.92 | PTGS1 (0.57) | HSD17B10TDP1CMA1PTGS1 | |
| Flomoxef SCHEMBL27896310 | 0.86 | PTGS1 (0.51) | HSD17B10TDP1CMA1PTGS1 | |
| SCHEMBL30515648 | 0.84 | CMA1 (0.60) | CMA1PTGS1 | |
| Flomoxef SCHEMBL30515667 | 0.80 | PTGS1 (0.44) | HSD17B10TDP1CMA1PTGS1 | |
| Moxalactam SCHEMBL30166493 | 0.74 | HSD17B10 (1.00) | HSD17B10TDP1CMA1PTGS1 | |
| Moxalactam SCHEMBL719333 | 0.74 | HSD17B10 (1.00) | HSD17B10TDP1CMA1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119355476-A | Test method and test device for bypass diode | 天合光能股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-116589483-A | Preparation method of high-purity flomoxef sodium for injection | 四川制药制剂有限公司 | 2023-08-15 | — | — | CN | disclosed |