Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 9/20 | 0.46 |
| ▸ | RAB9A | P51151 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637265 | 0.94 | METAP2 (0.60) | METAP2METAP1NPC1RAB9A | |
| SCHEMBL124356 | 0.83 | NPC1 (0.65) | HRH3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL29380975 | 0.83 | NPC1 (0.65) | HRH3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL127203 | 0.83 | NPC1 (0.65) | HRH3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL517344 | 0.83 | NPC1 (0.65) | HRH3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL8387722 | 0.83 | DEGS1 (0.53) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL28658639 | 0.83 | NPC1 (0.65) | HRH3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL22494493 | 0.82 | NPC1 (0.59) | HRH3KMT2AMEN1NPC1RAB9A | |
| SCHEMBL6639389 | 0.81 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL518025 | 0.81 | SMYD3 (0.63) | HRH3KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116589788-A | Toughness improvement method for thermal expansion microsphere foaming polypropylene material, and preparation method and application thereof | 华南理工大学 | 2023-08-15 | — | — | CN | claimed |