Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.56 |
| ▸ | HTR1A | P08908 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.56 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.56 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.56 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19687545 | 0.83 | TBXA2R (0.66) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL30516331 | 0.82 | CYP3A4 (0.49) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL28489505 | 0.80 | TBXA2R (0.85) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL28488241 | 0.80 | TBXA2R (0.85) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL28488243 | 0.79 | GAA (0.53) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| Hydrochloric Acid SCHEMBL28497871 | 0.78 | GAA (0.52) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL5459829 | 0.78 | TBXA2R (0.60) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL7308054 | 0.78 | TBXA2R (0.51) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL3377507 | 0.77 | CYP3A4 (0.61) | TBXA2RADRA1ASLC6A3ABCB11HTR1A | |
| SCHEMBL9761425 | 0.77 | TBXA2R (0.59) | TBXA2RADRA1ASLC6A3ABCB11HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112010801-B | Preparation method of amlodipine alkali | 山东汇海医药化工有限公司 | 2023-07-28 | — | — | CN | disclosed |