Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29051062 | 1.00 | KDM4E (0.37) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL28212789 | 0.85 | CHRNB2 (0.41) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL30339767 | 0.85 | CHRNB2 (0.41) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL30516405 | 0.82 | NFE2L2 (0.33) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL29051063 | 0.79 | HDAC1 (0.34) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL30516406 | 0.79 | HDAC1 (0.34) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL29051060 | 0.79 | HDAC1 (0.34) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL30516393 | 0.79 | HDAC1 (0.34) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL30516400 | 0.78 | KDM4E (0.38) | KDM4EPTGDR2POLBHTTCHRNB2 | |
| SCHEMBL30516399 | 0.78 | KDM4E (0.38) | KDM4EPTGDR2POLBHTTCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794449-B | Synthetic method of deuterated fumaric acid vorofacian metabolite | 广东东阳光药业有限公司 | 2023-08-04 | — | — | CN | disclosed |