Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24214081 | 1.00 | MAPK1 (0.37) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL24215525 | 0.85 | HDAC6 (0.33) | P2RX7HDAC6HDAC3HDAC4HDAC1 | |
| SCHEMBL24214080 | 0.85 | HCAR2 (0.36) | HDAC6HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL24215529 | 0.83 | RORC (0.33) | P2RX7 | |
| SCHEMBL20304715 | 0.79 | HDAC6 (0.34) | HDAC6HDAC3HDAC1HDAC2 | |
| SCHEMBL24215526 | 0.78 | ALDH1A1 (0.40) | POLBP2RX7CYP2C9ALDH1A1 | |
| SCHEMBL30516630 | 0.78 | ALDH1A1 (0.40) | POLBP2RX7CYP2C9ALDH1A1 | |
| SCHEMBL30412298 | 0.78 | — | — | |
| SCHEMBL38655680 | 0.77 | RORC (0.40) | MAPK1ATMPOLBKDM4EL3MBTL1 | |
| SCHEMBL24215455 | 0.75 | OPRK1 (0.45) | HDAC6CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116528862-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2023-08-01 | — | — | CN | disclosed |