Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516654 | 0.86 | HDAC1 (0.43) | HDAC1HPGDNPC1RAB9ACES2 | |
| SCHEMBL30516661 | 0.80 | NPC1 (0.42) | HPGDNPC1RAB9AMAPK10DAO | |
| SCHEMBL30516656 | 0.78 | TSHR (0.49) | HDAC1HPGDNPC1RAB9ATAS1R3 | |
| SCHEMBL30516632 | 0.77 | CNR2 (0.36) | HPGDNPC1RAB9APTGDR | |
| SCHEMBL30516651 | 0.74 | HDAC1 (0.50) | HDAC1HPGDNPC1RAB9ACES2 | |
| SCHEMBL30516637 | 0.72 | NPC1 (0.38) | NPC1RAB9A | |
| SCHEMBL30516655 | 0.72 | ALDH1A1 (0.31) | — | |
| SCHEMBL12181152 | 0.67 | HDAC1 (0.55) | HDAC1HPGDNPC1RAB9ACES2 | |
| SCHEMBL12181487 | 0.67 | HDAC1 (0.55) | HDAC1HPGDNPC1RAB9ACES2 | |
| SCHEMBL15296751 | 0.66 | HDAC1 (0.58) | HDAC1HPGDNPC1RAB9ACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |