Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 6/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516632 | 0.81 | CNR2 (0.36) | NPC1RAB9ACNR2 | |
| SCHEMBL30516655 | 0.81 | ALDH1A1 (0.31) | — | |
| SCHEMBL30516661 | 0.79 | NPC1 (0.42) | NPC1RAB9ANPSR1 | |
| SCHEMBL30516656 | 0.72 | TSHR (0.49) | NPC1RAB9ANPSR1 | |
| SCHEMBL30516667 | 0.72 | HDAC1 (0.40) | NPC1RAB9A | |
| SCHEMBL30135621 | 0.65 | CHRM2 (0.32) | — | |
| SCHEMBL13748344 | 0.63 | SMN1; SMN2 (0.49) | NPC1RAB9ACNR2NPSR1RXFP1 | |
| SCHEMBL2996683 | 0.59 | ALDH1A1 (0.44) | NPC1RAB9ANPSR1RXFP1 | |
| SCHEMBL11848005 | 0.59 | ALDH1A1 (0.44) | NPC1RAB9ANPSR1 | |
| SCHEMBL25439322 | 0.59 | SLC6A12 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |