Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30516667 | 0.80 | HDAC1 (0.40) | NPC1RAB9AMAPK10DAOHPGD | |
| SCHEMBL30516637 | 0.79 | NPC1 (0.38) | NPC1RAB9ANPSR1 | |
| SCHEMBL30516632 | 0.76 | CNR2 (0.36) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30516670 | 0.76 | NPC1 (0.49) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30516656 | 0.75 | TSHR (0.49) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30516655 | 0.74 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL12124368 | 0.69 | RAB9A (0.67) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12124461 | 0.69 | RAB9A (0.71) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12124434 | 0.69 | NPC1 (0.62) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12124462 | 0.68 | RAB9A (0.73) | NPC1RAB9AKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116529238-A | Novel prostaglandin E 2 Compounds with receptor inhibiting activity and uses thereof | 治纳辅医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |