Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | ECE1 | P42892 | 8/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29366452 | 0.92 | PCSK9 (0.52) | PRMT1PCSK9ACEOPRM1OPRD1 | |
| SCHEMBL30517374 | 0.88 | PCSK9 (0.46) | PRMT1PCSK9OPRM1OPRD1KMT2A | |
| SCHEMBL31130668 | 0.86 | CXCR4 (0.48) | PRMT1PCSK9OPRM1OPRD1 | |
| SCHEMBL30517378 | 0.86 | PCSK9 (0.45) | PRMT1PCSK9OPRM1OPRD1KMT2A | |
| SCHEMBL30517389 | 0.84 | OPRM1 (0.55) | PRMT1ACEOPRM1OPRD1ECE1 | |
| SCHEMBL30051121 | 0.84 | OPRM1 (0.56) | PRMT1ACEOPRM1OPRD1ECE1 | |
| SCHEMBL29683525 | 0.83 | ACE (0.56) | PRMT1ACEOPRM1OPRD1ECE1 | |
| SCHEMBL30310827 | 0.82 | ACE (0.62) | ACEECE1KMT2AL3MBTL1EDNRA | |
| SCHEMBL7402039 | 0.82 | MAGI3 (0.57) | PCSK9ACEECE1KMT2AL3MBTL1 | |
| SCHEMBL7402043 | 0.82 | MAGI3 (0.57) | PCSK9ACEECE1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230220001-A1 | METHOD FOR SYNTHESIS OF THIOETHER-CONTAINING PEPTIDES | HEIDELBERG PHARMA RESEARCH GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230220001-A1 | METHOD FOR SYNTHESIS OF THIOETHER-CONTAINING PEPTIDES | TST, PTMS, CTH | PRMT1 1142/4885PCSK9 2708/4885ACE 2020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.