Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054487 | 0.90 | MAOA (0.58) | MAOAMAOBITGB3ITGA2BNAAA | |
| SCHEMBL3056355 | 0.86 | CA2 (0.52) | NAAALMNAPTGER4PTGER2TSHR | |
| SCHEMBL3064345 | 0.82 | TSHR (0.49) | MAOAMAOBLMNAPTGER4PTGER2 | |
| SCHEMBL3051091 | 0.80 | CA2 (0.54) | NAAALMNA | |
| SCHEMBL3051707 | 0.80 | HRH3 (0.56) | HRH3LMNA | |
| SCHEMBL3050440 | 0.79 | NAAA (0.52) | NAAATSHR | |
| SCHEMBL3054858 | 0.77 | CA2 (0.53) | PTGER4PTGER2TSHR | |
| SCHEMBL3062372 | 0.77 | CA2 (0.54) | LMNA | |
| SCHEMBL3048192 | 0.75 | CA2 (0.65) | LMNA | |
| SCHEMBL27782264 | 0.75 | GHSR (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | claimed |
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | MAOA 2205/4885MAOB 1395/4885ITGB3 4504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.