Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL315303 | 0.84 | HDAC1 (0.69) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL6540023 | 0.78 | L3MBTL1 (0.51) | HDAC1HDAC6TSHR | |
| Phenylbutanoic Acid SCHEMBL21219015 | 0.75 | HDAC1 (1.00) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| Phenylbutanoic Acid SCHEMBL1021513 | 0.75 | HDAC1 (1.00) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| Phenylbutanoic Acid SCHEMBL1716 | 0.75 | HDAC1 (1.00) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL6208836 | 0.75 | SMN1; SMN2 (0.82) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL417360 | 0.74 | ALDH1A1 (0.62) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL1697834 | 0.74 | FFAR1 (0.68) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| 5-Phenylvaleric Acid SCHEMBL11500420 | 0.74 | MAPT (0.81) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 | |
| SCHEMBL13290714 | 0.74 | HDAC3 (0.62) | HDAC3MAPK1ADRA1AHDAC4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7744910-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7186414-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC (US) | 2007-03-06 | — | — | US | disclosed |
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECHNOLOGIES, INC. (US) | 2007-01-11 | — | — | US | disclosed |
| EP-1676832-A2 | Compounds and compositions for delivering active agents | Emisphere Technologies, Inc. (US) | 2006-07-05 | — | — | EP | disclosed |
| US-6991798-B1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010422-A1 | COMPOUNDS AND COMPOSITIONS FOR DELIVERING ACTIVE AGENTS | SERPINB1, ELANE, MMP8 | HDAC3 789/4885MAPK1 4522/4885ADRA1A 2614/4885 |
| US-20050272638-A1 | Compounds and compositions for delivering active agents | SERPINB1, ELANE, MMP8 | HDAC3 789/4885MAPK1 4522/4885ADRA1A 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.