Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | DHCR7 | Q9UBM7 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 2/20 | 0.43 |
| ▸ | MMP14 | P50281 | 2/20 | 0.43 |
| ▸ | MMP15 | P51511 | 2/20 | 0.43 |
| ▸ | MMP16 | P51512 | 2/20 | 0.43 |
| ▸ | MMP26 | Q9NRE1 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059107 | 0.89 | CYP11B1 (0.48) | CYP11B1CYP11B2PTGER2PDE4APDE4B | |
| SCHEMBL3051277 | 0.88 | MMP2 (0.46) | PDE4APDE4BPDE4CPDE4DKDM2B | |
| SCHEMBL3046225 | 0.88 | MMP2 (0.54) | PDE4APDE4BPDE4CPDE4DMMP1 | |
| SCHEMBL3050420 | 0.84 | MMP1 (0.44) | PTGER2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL13178635 | 0.83 | CYP11B1 (0.48) | CYP11B1CYP11B2PTGER2PDE4APDE4B | |
| SCHEMBL3051148 | 0.82 | CHRNA7 (0.48) | CYP11B1CYP11B2PTGER2PDE4APDE4B | |
| SCHEMBL3061756 | 0.81 | TSHR (0.48) | PDE4APDE4BPDE4CPDE4DKDM2B | |
| SCHEMBL3059224 | 0.79 | AKR1C3 (0.65) | PDE4BPDE4DDHCR7AKR1C3ALDH1A1 | |
| SCHEMBL3049285 | 0.77 | MMP2 (0.44) | PDE4APDE4BPDE4CPDE4DKDM2B | |
| SCHEMBL3051781 | 0.76 | PKM (0.48) | PDE4APDE4BPDE4CPDE4DMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | claimed |
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | CYP11B1 98/4885CYP11B2 71/4885PTGER2 2377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.