Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 4/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084634 | 0.85 | ALDH1A1 (0.36) | ADRA1DADRA1AADRA1BALDH1A1LMNA | |
| SCHEMBL34469514 | 0.80 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL2587303 | 0.80 | ADRA1D (0.34) | ADRA1DADRA1AADRA1BDRD2 | |
| SCHEMBL14995111 | 0.78 | P2RX7 (0.34) | ADRA1DADRA1AADRA1B | |
| SCHEMBL17685652 | 0.78 | C5AR1 (0.33) | ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL34469822 | 0.78 | C5AR1 (0.33) | ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL3443411 | 0.77 | MAPT (0.32) | ADRA1DADRA1AADRA1BMEN1MAPT | |
| SCHEMBL135939 | 0.77 | MAPT (0.32) | MAPTTP53AR | |
| SCHEMBL29365624 | 0.77 | MAPT (0.32) | MAPTTP53AR | |
| Hydrochloric Acid SCHEMBL2833170 | 0.76 | MAPT (0.32) | MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116600803-A | Macrocyclic urea orexin receptor agonists | 默沙东有限责任公司 | 2023-08-15 | — | — | CN | disclosed |