SCHEMBL135939

SCHEMBL135939

Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)C2=[Ru](Cl)(Cl)=Cc2ccccc2OC(C)C)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
TP53 P04637 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29365624 1.00 MAPT (0.32) MAPTTP53AR
Hydrochloric Acid SCHEMBL2833170 0.99 MAPT (0.32) MAPTTP53
SCHEMBL15612708 0.87 HPGD (0.32) MAPT
SCHEMBL29861617 0.87 HPGD (0.32) MAPT
SCHEMBL1195613 0.87 ALOX5 (0.36)
SCHEMBL1244265 0.87 SMN1; SMN2 (0.33) MAPT
SCHEMBL16390254 0.86 HPGD (0.35) MAPT
SCHEMBL34469514 0.85 ADRA1D (0.34)
SCHEMBL2587303 0.85 ADRA1D (0.34)
SCHEMBL15525571 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080282-A Preparation method of cyclic polyolefin 2026-05-26 CN claimed
US-12612352-B2 Process for preparing perfuming intermediate FIRMENICH SA (CH) 2026-04-28 US claimed
EP-3411046-B1 RAPAGLUTINS, NOVEL INHIBITORS OF GLUT AND USE THEREOF UNIV JOHNS HOPKINS (US) 2025-07-16 EP claimed
US-20250179091-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMA (US) 2025-06-05 US claimed
CN-117229451-B Polynorbornene-based crosslinked anion exchange membrane and preparation method and application thereof 北京清玮膜科技有限公司 2025-03-28 CN claimed
CN-119569997-A Ionic polynorbornene crosslinked anion exchange membrane and preparation method and application thereof 北京清玮膜科技有限公司 2025-03-07 CN claimed
CN-119219898-A Preparation method of degradable recycled plastic 浙江大学 2024-12-31 CN claimed
US-20240368068-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATES FIRMENICH SA (CH) 2024-11-07 US claimed
CN-118702842-A Preparation method of liquid styrene-butadiene rubber 青岛科技大学 2024-09-27 CN claimed
WO-2024186647-A1 METHODS FOR CONVERTING POLYVINYL CHLORIDE TO SMALLER MOLECULES USING OLEFIN CROSS METATHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-09-12 WO claimed
US-7550607-B2 Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses AUSPEX PHARMACEUTICAL, INC. (US) 2009-06-23 US claimed
US-7534917-B1 Method of producing dicarboxylic acids THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2009-05-19 US claimed
US-20080227851-A1 LAULIMALIDE AND LAULIMALIDE ANALOGS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-09-18 US claimed
EP-1935893-A1 TOTAL SYNTHESIS OF PLADIENOLIDE B AND PLADIENOLIDE D Eisai R&D Management Co., Ltd. (JP) 2008-06-25 EP claimed
US-20080021226-A1 Process for total synthesis of pladienolide B and pladienolide D EISAI R&D MANAGEMENT CO., LTD. 2008-01-24 US claimed
EP-1594835-A4 METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES AUSPEX PHARMACEUTICALS INC (US) 2007-05-02 EP claimed
US-20060173199-A1 Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses HONG BORCHERNG 2006-08-03 US claimed
US-20060035822-A1 Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases ARRAY BIOPHARMA INC. 2006-02-16 US claimed
EP-1594835-A2 METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES Auspex Pharmaceuticals, Inc. (US) 2005-11-16 EP claimed
WO-2004064745-A2 METHOD OF PREPARATION OF HETEROCYCLIC MOLECULES WITH PHARMACEUTICAL PHARMACEUTICAL EXCIPIENT COSMECEUTICAL AGROCHEMICAL AND INDUSTRIAL USES AUSPEX PHARMACEUTICALS, INC. (US) 2004-08-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080227851-A1 LAULIMALIDE AND LAULIMALIDE ANALOGS SSB, LPXN, LTA MAPT 4137/4885TP53 3013/4885AR 4444/4885
US-12612352-B2 Process for preparing perfuming intermediate CBR1, CYP2E1, CBR3 MAPT 4509/4885TP53 3815/4885AR 4122/4885
US-20250179091-A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1G, SCNN1B MAPT 4877/4885TP53 3907/4885AR 4693/4885
US-20060173199-A1 Method of preparation of heterocyclic molecules with pharmaceutical, pharmaceutical excipient, cosmeceutical, agrochemical and industrial uses LSS, DHPS, CYP51A1 MAPT 2419/4885TP53 994/4885AR 2935/4885
US-20240368068-A1 PROCESS FOR PREPARING PERFUMING INTERMEDIATES POR, PPOX, ACLY MAPT 3596/4885TP53 3282/4885AR 4820/4885
US-20080021226-A1 Process for total synthesis of pladienolide B and pladienolide D TPD52L2, CYP8B1, HPD MAPT 4788/4885TP53 547/4885AR 1006/4885
US-20060035822-A1 Cyclosporin analogs for the treatment of immunoregulatory disorders and respiratory diseases TSLP, CHP1, IL2 MAPT 4573/4885TP53 1498/4885AR 4262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.